{"id":92,"date":"2024-10-11T02:53:29","date_gmt":"2024-10-11T02:53:29","guid":{"rendered":"https:\/\/flocian.com\/?page_id=92"},"modified":"2025-08-24T21:42:35","modified_gmt":"2025-08-24T21:42:35","slug":"accomplishments","status":"publish","type":"page","link":"https:\/\/flocian.com\/index.php\/accomplishments\/","title":{"rendered":"Accomplishments"},"content":{"rendered":"\n<div class=\"wp-block-group alignfull is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-23441af8 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-large is-resized has-custom-border is-style-rounded is-style-rounded--1\"><img loading=\"lazy\" decoding=\"async\" width=\"1111\" height=\"558\" src=\"https:\/\/flocian.com\/wp-content\/uploads\/2024\/12\/six-edited.png\" alt=\"\" class=\"wp-image-251\" style=\"border-radius:20px;width:744px;height:auto\" srcset=\"https:\/\/flocian.com\/wp-content\/uploads\/2024\/12\/six-edited.png 1111w, https:\/\/flocian.com\/wp-content\/uploads\/2024\/12\/six-edited-300x151.png 300w, https:\/\/flocian.com\/wp-content\/uploads\/2024\/12\/six-edited-1024x514.png 1024w, https:\/\/flocian.com\/wp-content\/uploads\/2024\/12\/six-edited-768x386.png 768w\" sizes=\"auto, (max-width: 1111px) 100vw, 1111px\" \/><figcaption class=\"wp-element-caption\">Mouse brain cortex: <strong><mark style=\"background-color:rgba(0, 0, 0, 0);color:#ff0000\" class=\"has-inline-color\">red<\/mark><\/strong>: tomato lectin (vessels), <strong><mark style=\"background-color:rgba(0, 0, 0, 0);color:#064e10\" class=\"has-inline-color\">green<\/mark><\/strong>: Arl13b-GFP (cilia).<br>Dr. Kevin Rarick, Medical College of Wisconsin<\/figcaption><\/figure>\n<\/div>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Our success so far&#8230;<\/h2>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Publications <\/h4>\n\n\n\n<p>The cilia concept that forms the basis of our company is published in multiple in leading biomedical research journals.&nbsp;<\/p>\n\n\n\n<ul style=\"line-height:1.6\" class=\"wp-block-list is-style-default has-medium-font-size\">\n<li style=\"margin-top:var(--wp--preset--spacing--10);margin-bottom:var(--wp--preset--spacing--10)\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30571172\/\" data-type=\"link\" data-id=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30571172\/\">Eisa-Beygi S, Benslimane FM, El-Rass S, Prabhudesai S, Khatib Ali Abdelrasool M, Simpson PM, Yalcin HC, Burrows PE and <strong>Ramchandran R<\/strong>. Characterization of endothelial cilia distribution during cerebral-vascular development in zebrafish (<em>danio rerio<\/em>)***. 2018. ATVB. PMID:&nbsp; 30571172. **Inside ATVB editorial: Before the Pump: The Importance of Cilia in Cranial Development.&nbsp;<\/a><\/li>\n\n\n\n<li style=\"margin-top:var(--wp--preset--spacing--10);margin-bottom:var(--wp--preset--spacing--10)\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35143420\/\" data-type=\"link\" data-id=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35143420\/\">Gupta A, Thirugnanam K, Thamilarasan M, Mohieldin AM, Al-Jighefee HT, Prabhudesai S, Griffin M, Spearman AD, Pan A, Palecek SP, Yalcin HC, Nauli SM, Rarick K, Zennadi R and <strong>Ramchandran R<\/strong>. Cilia proteins are biomarkers of altered flow in the vasculature. 2022. JCI Insight. PMID: 351433420.<\/a><\/li>\n\n\n\n<li style=\"margin-top:var(--wp--preset--spacing--10);margin-bottom:var(--wp--preset--spacing--10)\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35700757\/\" data-type=\"link\" data-id=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35700757\/\">Thirugnanam K, Prabhudesai S, Van Why E, Pan A, Gupta A, Foreman K, Zennadi R, Rarick KR, Nauli SM, Palecek SP and <strong>Ramchandran R<\/strong>. Ciliogenesis mechanisms mediated by PAK2-ARL13B signaling in brain endothelial cells is responsible for vascular stability. 2022. Biochemical Pharmacology. PMID: 35700757.<\/a>&nbsp;<\/li>\n\n\n\n<li style=\"margin-top:var(--wp--preset--spacing--10);margin-bottom:var(--wp--preset--spacing--10)\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38028541\/\" data-type=\"link\" data-id=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38028541\/\">Thirugnanam K, Gupta A, Nunez F, Prabhudesai SP, Pan AY, Nauli S, <strong>Ramchandran R<\/strong>. Brain microvascular endothelial cells possess a second cilium from the daughter centriole. 2023. Frontiers in Molecular Biosciences. PMID: 38028541.<\/a>&nbsp;<\/li>\n\n\n\n<li><a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jproteome.5c00168\">Mohieldin AM, Spencer M, Bernal C, Fadol WB, Gupta A, Thirugnanam K, Delahunty C, Nunez F, Pan A, Palecek SP, Rarick KR, <strong>Ramchandran R<\/strong>, Zennadi R, Yates J, Nauli SM. Cilia Proteome as Biomarker for Underlying Vascular Injury in Sickle Cell Disease. 2025. Journal of Proteome Research***. PMID: 40374167<\/a><\/li>\n<\/ul>\n\n\n\n<div style=\"height:48px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Funding<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li style=\"margin-top:var(--wp--preset--spacing--10);margin-bottom:var(--wp--preset--spacing--10)\">Cilia Biomarker Kit Development for Brain Injury Diagnosis and Prognosis, 1R41 NS139906-01A1, STTR Phase I, 2 years, $699,000.\u00a0<\/li>\n<\/ul>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Our success so far&#8230; Publications The cilia concept that forms the basis of our company is published in multiple in leading biomedical research journals.&nbsp; Funding<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-92","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/flocian.com\/index.php\/wp-json\/wp\/v2\/pages\/92","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/flocian.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/flocian.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/flocian.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/flocian.com\/index.php\/wp-json\/wp\/v2\/comments?post=92"}],"version-history":[{"count":6,"href":"https:\/\/flocian.com\/index.php\/wp-json\/wp\/v2\/pages\/92\/revisions"}],"predecessor-version":[{"id":324,"href":"https:\/\/flocian.com\/index.php\/wp-json\/wp\/v2\/pages\/92\/revisions\/324"}],"wp:attachment":[{"href":"https:\/\/flocian.com\/index.php\/wp-json\/wp\/v2\/media?parent=92"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}