Cian

Mouse brain cortex: cyan: GFAP (astrocytes), blue (nuclei), green: Arl13b-GFP (cilia).
Credit : Dr. Kevin Rarick, Medical College of Wisconsin

Our Goals

Vascular Disease Insights

Understand the basic mechanisms that underlies endothelial cilia rote in vascular injury

Cilia-Based Therapeutics

Develop therapeutics for vascular related conditions based on cilia and proteins expressed in cilia

Ciliary Biomarker Diagnostics

Develop ciliary biomarkers for diagnosing disease severity and prognosticating disease related clinical outcomes

What we do

Investigation of Cilia Functions

We investigate the multifaceted roles of cilia in brain blood vessel development and their implications for neurovascular health.

Development of Diagnostic Tools

Our research aims to create innovative diagnostic tools using cilia as biomarkers for assessing vascular health and identifying diseases.

Development of Prognostication Tools

Creating innovative tools to predict disease progression and outcomes by analyzing ciliary protein biomarkers associated with vascular health.

Exploration of Therapeutic Approaches

We explore therapeutic strategies to enhance vascular stability, focusing on the role of proteins involved in ciliogenesis and their potential to improve brain injury outcomes.